Synthesis and Antimicrobial Activity of Transition Metal Trimesate Complexes with Hydrazine

Abstract

Novel complexes of Mn(II), Co(II), Ni(II), Cu(II), and Zn(II) with trimesic acid (benzene-1,3,5-tricarboxylic acid) and hydrazine were synthesized and characterized. The complexes exhibited octahedral geometry, confirmed through electronic, FTIR, Raman, and EPR spectroscopic analyses. Thermal studies showed stepwise decomposition to form stable metal oxides, highlighting their potential as precursors for nanoparticle synthesis. Antibacterial and antifungal activity evaluations revealed that Zn(II) and Cu(II) complexes exhibited significant bioactivity against tested microbes, surpassing the free ligand. The study demonstrates the potential of these metal complexes for pharmaceutical and nanomaterial applications.